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A DOUBLE‐BLIND CONTROLLED EVALUATION OF DIPROSONE CREAM 0.05% IN COMPARISON WITH SYNALAR CREAM 0.01% IN THE TREATMENT OF PSORIASIS AND OTHER STEROID RESPONSIVE DERMATOSES
Author(s) -
Lewis M. B.
Publication year - 1978
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1978.tb00195.x
Subject(s) - medicine , psoriasis , double blind , double blind study , dermatology , significant difference , topical steroid , alternative medicine , pathology , placebo
S ummary A three‐week double‐blind randomized study was carried out to compare the effect of Diprosone cream 0.05% with Synalar cream 0.01%. Forty patients suffering from psoriasis and other steroid responsive dermatoses were included in the study. The disease status was carefully monitored throughout the period of the study and parameters were measured to determine the efficacy, onset of action, tolerance and cosmetic acceptability of the two preparations under study. It was concluded that both preparations were efficacious in the treatment of psoriasis and other steroid responsive dermatoses, and that there was no statistically significant difference between the two preparations in the parameters evaluated, other than in the treatment of psoriasis when the parameter of scaling was measured. Side effects were recorded in two patients receiving Synalar, and one receiving Diprosone, during this study.