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SKIN MICROVASCULAR LESIONS IN CHRONIC DIFFUSE HEPATIC DISEASES
Author(s) -
Valdes Eduardo F.,
Herrero Maria V.,
Calb I.,
Bello Carmen
Publication year - 1977
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1111/j.1440-0960.1977.tb00729.x
Subject(s) - medicine , pathology , dermatology
S mmary Skin biopsies obtained from the hand have been evaluated by histological and histochemical techniques, in twenty patients with a confirmed diagnosis of chronic diffuse hepatopathies and in ten healthy controls. In patients with chronic hepatic disease, skin biopsies show microvascular lesions, characterized by thickening of the PAS‐positive basement membrane and endothelial alterations, similar to those found in diabetic patients. These lesions did not exist in the healthy control group.