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Inhibin‐α Immunohistochemical Expression in Mature and Immature Canine Sertoli and Leydig Cells
Author(s) -
Grieco V,
Banco B,
Ferrari A,
Rota A,
Faustini M,
Veronesi MC
Publication year - 2011
Publication title -
reproduction in domestic animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 66
eISSN - 1439-0531
pISSN - 0936-6768
DOI - 10.1111/j.1439-0531.2011.01784.x
Subject(s) - sertoli cell , immunohistochemistry , biology , leydig cell , andrology , endocrinology , medicine , spermatogenesis , hormone , luteinizing hormone , immunology
Contents Formalin‐fixed, paraffin‐embedded sections from 32 canine pairs of testes were immunohistochemically examined for Inhibin‐α (INHα). Samples were subdivided into two groups (group 1, neonates; group 2, puppies and adults) and results statistically compared. Inhibin‐α was significantly expressed only in Sertoli cells of neonatal testes, while in Leydig cells it was expressed without significant difference between groups. These results suggest that, in dogs, INHα expression switches from Sertoli to Leydig cells during testicular maturation and that, in adult, Leydig cells represent the main source of INHα.