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SRY ‐Negative XX Sex Reversal in a French Bulldog
Author(s) -
Campos M,
MorenoManzano V,
GarcíaRoselló M,
GarcíaRoselló E
Publication year - 2011
Publication title -
reproduction in domestic animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 66
eISSN - 1439-0531
pISSN - 0936-6768
DOI - 10.1111/j.1439-0531.2010.01612.x
Subject(s) - testis determining factor , sex reversal , karyotype , biology , disorders of sex development , histology , y chromosome , physiology , medicine , genetics , gene , chromosome
Contents Here, we describe a 3‐month‐old XX male French Bulldog. The diagnosis was based on the clinical signs, gonadal histology and cytogenetic analysis. Additionally, the dog was confirmed to be Sry negative by semi‐quantitative reverse transcription polymerase chain reaction (sqRT‐PCR). Canine Sry ‐negative XX sex reversal is a disorder of gonadal development where individuals who have a female karyotype develop testes or ovotestes. To our knowledge, this case is the first XX male sex reversion described in a French Bulldog.