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Effects of Chloroformic Extracts from Washed and Unwashed Papaya Seeds ( Carica papaya ) on the Sperm Concentration of Dogs
Author(s) -
OrtegaPacheco A,
JiménezCoello M,
GutiérrezBlanco E,
AcostaViana KY,
GuzmánMarín E,
ZavalaSánchez MA,
MontalvoBeltrán NE,
PérezGutiérrez MS
Publication year - 2010
Publication title -
reproduction in domestic animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 66
eISSN - 1439-0531
pISSN - 0936-6768
DOI - 10.1111/j.1439-0531.2009.01503.x
Subject(s) - carica , sperm , biology , traditional medicine , spermatogenesis , botany , medicine , endocrinology
Contents Papaya seeds ( Carica papaya Linn) have been found to have a significant effect on sperm characteristics in some mammals, including humans, but no studies have investigated the effects on dogs. In the present study, a significant decrease in sperm concentration was observed in a group of dogs treated with extracts from washed papaya seeds, but no decrease was observed in the group of dogs treated with non‐washed seeds. An important effect of extract components from washed seeds such as fatty acids is probably involved in the reduction of sperm production because of Sertoli cell damage, as has been suggested for langur monkeys. Dilution of the active components in the non‐washed papaya seeds or interference with some of the components may reduce the expected effect on spermatogenesis. This first report on the effects of a chloroformic extract of papaya seeds in dogs suggests that an increased dose is necessary to achieve azoospermia.