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Production of Transgenic Farm Animals by Viral Vector‐Mediated Gene Transfer
Author(s) -
Whitelaw CBA,
Lillico SG,
King T
Publication year - 2008
Publication title -
reproduction in domestic animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 66
eISSN - 1439-0531
pISSN - 0936-6768
DOI - 10.1111/j.1439-0531.2008.01184.x
Subject(s) - gene transfer , transgene , vector (molecular biology) , biology , gene , virology , viral vector , genetics , recombinant dna
Contents Transgenic technology holds considerable promise to advance understanding in biomedical and agricultural systems with some believing that one day transgenic animals may directly contribute to farming and breeding practice. Nevertheless, applications in livestock have been restricted in part by the inefficiency of the technology. The recent development of lentivirus vectors for transgene delivery may overcome some of this limitation. This presentation describes these vectors, their advantages and limitations.