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Effect of Progesterone Supplementation During Early Foetal Period in Neospora caninum Seropositive Dairy Cows
Author(s) -
BechSàbat G,
Serrano B,
GarcíaIspierto I,
Santolaria P,
Yániz J,
Almería S,
LópezGatius F
Publication year - 2006
Publication title -
reproduction in domestic animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 66
eISSN - 1439-0531
pISSN - 0936-6768
DOI - 10.1111/j.1439-0531.2006.00774_1_8.x
Subject(s) - neospora caninum , gestation , abortion , medicine , pregnancy , herd , obstetrics , neospora , gynecology , zoology , biology , veterinary medicine , immunology , antibody , toxoplasma gondii , genetics
Neospora caninum infection is a major risk factor for abortion in cattle. The aim of this study was to evaluate the influence of progesterone supplementation from days 35 to 63 of gestation on abortion in 351 N. caninum seropositive dairy cows. Animals were assigned randomly to Treatment (n = 180), receiving progesterone with an intravaginal device (PRID) fitted at pregnancy diagnosis (day 35), or to Control group (n = 171). Total abortions were similar for both groups (30% vs 29% for the Control and Treatment group, respectively). Logistic regression procedures were performed using abortion before or after Day 90 of gestation as the dependent variables, and herd, parity (primiparous vs multiparaous), season (cold vs warm period) and treatment as factors. Any variable fitted the model for abortion after Day 90 of gestation, whereas parity, season and treatment had significant effects (p = 0.71, the Hosmer and Lemeshow model fits) on pregnancy loss before Day 90 with odds ratios of 2.9 (multiparous vs primiparous), 4.7 (warm vs cold season) and 0.29 (treatment vs control). Our results showed that progesterone supplementation during the early foetal period in seropositive cows reduced 3.4 (1/0.29) times the risk of abortion during the first trimester of gestation, as previously reported in seronegative animals (López‐Gatius et al. 2004, Theriogenology 62: 1529–1535), but treatment had not effect on the subsequent abortion rate.