Premium
Emerging moulds: epidemiological trends and antifungal resistance
Author(s) -
Miceli Marisa H.,
Lee Samuel A.
Publication year - 2011
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2011.02032.x
Subject(s) - mucorales , antifungal , epidemiology , aspergillus , intensive care medicine , voriconazole , fusarium , antifungal drugs , population , biology , medicine , mucormycosis , microbiology and biotechnology , environmental health , pathology , horticulture
Summary Invasive fungal infections (IFIs) are associated with high morbidity and mortality in immunocompromised patients. Although Aspergillus spp. remain an important cause of IFI, other moulds such as Fusarium spp., dematiaceous fungi and Mucorales have become increasingly prevalent among this patient population. Diagnosis and treatment of invasive mould infections remain a challenge. Because of the poor prognosis associated with IFIs, understanding the activity, efficacy and limitations of the available drugs is critical to select the appropriate antifungal agent on an individualised basis.