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Determination of antidermatophytic effects of non‐steroidal anti‐inflammatory drugs on Trichophyton mentagrophytes and Epidermophyton floccosum
Author(s) -
AlJanabi Ali Abdul Hussein S.
Publication year - 2011
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2010.01945.x
Subject(s) - epidermophyton floccosum , trichophyton , diclofenac , naproxen , pharmacology , analgesic , aspirin , anti inflammatory , traditional medicine , chemistry , medicine , microbiology and biotechnology , biology , antifungal , biochemistry , alternative medicine , pathology
Summary Non‐steroidal anti‐inflammatory drugs (NSAIDs) are one of the most common pharmacological agents. They have three primary therapeutic properties including anti‐inflammatory, anti‐pyretic and analgesic effects. Seven NSAIDs were tested against two species of dermatophytes. Percentage inhibition was determined for effective agents. Diclofenac, aspirin and naproxen showed more potential to inhibit the growth of dermatophytes. Epidermophyton floccosum revealed susceptibility to more number of the tested agents than Trichophyton mentagrophytes . In conclusion, many NSAIDs may have a high potential to inhibit the growth of dermatophytes, while some of the agents belonging to this pharmaceutical group used in this study showed a potential activity on tested fungi.