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Cutaneous hyalohyphomycosis by Scedosporium apiospermum in an immunocompromised patient
Author(s) -
Makino Koji,
Fukushima Satoshi,
Maruo Keishi,
Egawa Kiyofumi,
Nishimoto Katsutaro,
Ihn Hironobu
Publication year - 2011
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2009.01797.x
Subject(s) - scedosporium apiospermum , itraconazole , hyaline , terbinafine , actinomycosis , mycosis , medicine , nocardiosis , septate , phaeohyphomycosis , biology , pathology , dermatology , antifungal , nocardia , surgery , voriconazole , paleontology , bacteria , genetics
Summary S cedosporium apiospermum is a ubiquitous filamentous fungus that may infect immunocompetent patients after trauma and may cause severe and often fatal infections in immunocompromised hosts. Here, we present the case of a 28‐year‐old female with S. apiospermum infection on the left forearm that had developed while she was on long‐term immunosuppressant therapy. Analysis of a skin biopsy specimen showed a mixed cell granuloma with hyaline septate hyphae. Culture of the abscess revealed S. apiospermum which was identified as S. apiospermum sensu stricto by sequencing of the internal transcribed spacer‐1 region of ribosomal DNA genes. Resection of the eruption and oral itraconazole (100 mg day −1 ) therapy for 4 months was effective in curing the infection.