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Primary cutaneous cryptococcosis in a renal transplant recipient: case report
Author(s) -
Zorman Jerneja Videčnik,
Zupanc Tatjana Lejko,
Parač Zlatko,
Čuček Igor
Publication year - 2010
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2009.01737.x
Subject(s) - cellulitis , medicine , cryptococcosis , cryptococcus neoformans , necrotising fasciitis , differential diagnosis , fasciitis , dermatology , antibiotics , soft tissue , cryptococcus , surgery , pathology , biology , microbiology and biotechnology
Summary We report a kidney transplant recipient with severe skin‐ and soft‐tissue infection mimicking necrotising fasciitis. Patient failed to respond to empirical antibiotic therapy for presumed bacterial cellulitis. Culture of aspirate from the wound and tissue samples revealed Cryptococcus neoformans . No signs of systemic cryptococcal infection were found. After antifungal treatment and surgical intervention, complete healing was achieved. Clinical and microbiological characteristics of this patient are discussed. Our case indicates that primary cutaneous cryptococcosis must be included in the differential diagnosis of severe cellulitis in solid organ transplant recipients not responding to broad‐spectrum antibiotic regimens. In our case, prompt diagnosis and treatment could dramatically modify the outcome.