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Laryngeal histoplasmosis in an immunocompetent patient from a non‐endemic region: case report
Author(s) -
Ferrari Teresa C. A.,
Soares João Marcos A.,
Salles José Maria P.,
Handam Júnia S.,
Azevedo Rosana C. S.,
Xavier Marcelo A. P.,
Faria Luciana C.
Publication year - 2009
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2008.01650.x
Subject(s) - histoplasmosis , medicine , laryngoscopy , larynx , throat , lesion , dermatology , amphotericin b , histoplasma , histoplasma capsulatum , mycosis , surgery , antifungal , intubation
Abstract Histoplasma capsulatum infection involving the larynx is a rare manifestation, especially in immunocompetent individuals and a high index of suspicion is needed to establish the diagnosis correctly. We report a case of a 50‐year‐old Brazilian man who presented with progressive hoarseness and throat pain for 4 months. Laryngoscopy showed a supraglottic vegetant lesion, and the biopsies chronic granulomatous inflammation without any specific agent. A second laryngoscopy with biopsies was performed and after 17 days of incubation in specific medium, H. capsulatum was isolated. The patient was successfully treated with amphotericin B.