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Current practice of antifungal prophylaxis and treatment in immunocompromised children and adults with malignancies: a single centre approach
Author(s) -
Lehrnbecher Thomas,
Mousset Sabine,
Sörensen Jan,
Böhme Angelika
Publication year - 2009
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2008.01629.x
Subject(s) - antifungal , medicine , hematology , intensive care medicine , hematopoietic stem cell transplantation , transplantation , pediatric oncology , hematopoietic cell , pediatrics , cancer , antifungal drugs , stem cell , haematopoiesis , dermatology , biology , genetics
Summary Although various guidelines on antifungal prophylaxis and treatment have been published, the practical approach in the individual clinical setting might considerably differ because of special local circumstances. In addition, there are major differences between paediatric and adult patients regarding antifungal strategies and the use of antifungal compounds. We here present the antifungal approach in the Departments of Hematology and Oncology of the University Hospital of Frankfurt, where per year approximately 350 children and adults are diagnosed with cancer and an additional 100 patients undergo haematopoietic stem cell transplantation. The differences in the approach between the paediatric and adult setting are highlighted.