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Isolation of Aspergillus udagawae from a fatal case of feline orbital aspergillosis
Author(s) -
Kano Rui,
Itamoto Kazuhito,
Okuda Masaru,
Inokuma Hisashi,
Hasegawa Atsuhiko,
Balajee S. Arunmozhi
Publication year - 2008
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2008.01493.x
Subject(s) - aspergillosis , aspergillus fumigatus , amphotericin b , aspergillus , microbiology and biotechnology , biology , fungal pathogen , isolation (microbiology) , pathogen , mycosis , opportunistic pathogen , antifungal , immunology , pseudomonas aeruginosa , genetics , bacteria
Summary Aspergillus fumigatus is the predominant etiological agent of sino‐orbital aspergillosis in humans and animals. Here we report for the first time A. udagawae , a previously recognised but rare opportunistic pathogen causing fatal orbital aspergillosis in a cat. Identification of this isolate was secured by comparative sequence based analyses of the ITS and the β tubulin region. Antifungal susceptibility testing results revealed that this isolate had high in vitro MIC to amphotericin B (AMB) that correlated with in vivo failure of therapy with AMB.