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Successful treatment of disseminated mucormycosis with a combination of liposomal amphotericin B and posaconazole in a patient with acute myeloid leukaemia
Author(s) -
Rickerts V.,
Atta J.,
Herrmann S.,
Jacobi V.,
Lambrecht E.,
Bialek R.,
JustNübling G.
Publication year - 2006
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2006.01299.x
Subject(s) - posaconazole , mucormycosis , amphotericin b , medicine , antifungal , zygomycosis , myeloid leukaemia , surgery , dermatology
The combination of resection of infected tissue and antifungal therapy is the treatment of choice in mucormycosis. In disseminated mucormycosis, where surgery is impossible, the mortality is almost 90%. We report the first case of disseminated mucormycosis that was cured with a combination therapy of liposomal amphotericin B and posaconazole without surgical intervention.