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Successful caspofungin treatment of multidrug resistant Candida parapsilosis septicaemia in an extremely low birth weight neonate
Author(s) -
Yalaz Mehmet,
Akisu Mete,
Hilmioglu Suleyha,
Calkavur Sebnem,
Cakmak Bilin,
Kultursay Nilgun
Publication year - 2006
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2006.01220.x
Subject(s) - caspofungin , fluconazole , candida parapsilosis , low birth weight , amphotericin b , medicine , adverse effect , gestational age , birth weight , microbiology and biotechnology , antifungal , biology , pregnancy , genetics
Summary Candida septicaemia with multidrug resistance is an uncommon event in preterm neonates. We present an extremely low birth weight infant (gestational age of 27 weeks, birth weight of 980 g) who developed congenital Candida parapsilosis septicaemia. Because the fungus was resistant both to amphotericin B and fluconazole, caspofungin was chosen for therapy. The fungus was successfully eradicated without any clinical or laboratory adverse effects.