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In vitro adhesion of Candida species to denture base materials
Author(s) -
He X. Y.,
Meurman J. H.,
Kari K.,
Rautemaa R.,
Samaranayake L. P.
Publication year - 2006
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.2006.01189.x
Subject(s) - candida krusei , candida albicans , adhesion , corpus albicans , candida glabrata , stomatitis , candida dubliniensis , microbiology and biotechnology , in vitro , chemistry , biology , materials science , medicine , composite material , biochemistry , dermatology
Summary Adhesion of Candida species to prosthetic acrylic resins is an essential first step in the pathogenesis of denture stomatitis. Data on the relative adhesion of pathogenic non‐ albicans Candida species to different denture base materials are sparse. The purpose of the present study was to investigate in vitro adhesion of C. albicans , C. glabrata , C. krusei and C. dubliniensis to four different denture base materials. Specimens of both heat‐cured resins (Vertex TM Rapid Simplified and ProBase TM Hot) and cold‐cured resins (Paladur ® A and Paladur ® B) were prepared using a novel method and the adhesion of four strains each of the foregoing Candida species evaluated microscopically using a soft imaging system . There was a significant difference in yeast adherence between Vertex and the other resins. Only C. glabrata attached to Vertex, while all the remainder of the tested species adhered to all other resins tested except ProBase, which resisted C. krusei adhesion. There was a significant difference in candidal adhesion between cold‐cured and heat‐cured resins for three Candida species ( C. albicans , P = 0.039; C. glabrata , P = 0.002 and C. krusei , P = 0.000). The type of denture base material and whether they are heat‐cured or cold‐cured play an important role in modifying candidal adhesion.