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In vitro antifungal activity of Polyporaceae against yeasts and dermatophytes
Author(s) -
Steinmetz M.D.,
Rascol J.P.,
Régli P.,
Gargadennec A.,
Andary C.
Publication year - 1995
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.1995.tb00413.x
Subject(s) - microsporum canis , epidermophyton floccosum , microbiology and biotechnology , microsporum gypseum , dermatophyte , trichophyton rubrum , biology , polyporaceae , trichophyton , candida albicans , microsporum , agar dilution , antifungal , antimicrobial , botany , minimum inhibitory concentration
Summary. The antifungal activity of 38 Polyporaceae sensu lato against yeasts and dermatophytes was tested in vitro by the agar dilution method. Strains were typed organisms and clinical isolates. In this first report Pycnoporellus fulgens (Fr. Donk was found to be the most active species against pathological fungi and showed broad‐spectrum antifungal activity against yeasts ( Candida albicans, Candida glabrata ) and dermatophytes ( Trichophyton mentagrophytes, Trichophyton rubrum. Microsporum canis. Microsporum gypseum. Epidermophyton floccosum ). Other Polyporaceae species also showed antifungal activity, but only against dermatophytes. Zusammenfassung. Alkoholische Rohextrakte von 38 Polyporaceae‐Arten wurden in vitro mittels Agardilutiontest auf ihre antimyzetische Wirkung gegen Hefen und Dermatophyten geprüft. Die Teststämme waren einige Sammlungsstämme, in der Mehrzahl aber klinische Isolate. In dieser Studie erwies sich der Extrakt von Pycnoporellus fulgens (Fr.) Donk als antimyzetisch aktivste Spezies gegen pathogene Hefen ( Candida albicans, C. glabrata ) sowie gegen Dermatophyten ( Trichophyton mentagrophytes, T. rubrum, Microsporum canis, M. gypseum, Epidermophyion floccosum ). Andere Polyporaceae zeigten ebenfalls antimyzetische Aktivitat, jedoch nur gegen Dermatophyten.