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Infection due to Cryptococcus neoformans of unusual morphology in a patient with AIDS
Author(s) -
Anandi V.,
Babu P. G.,
John T. J.
Publication year - 1991
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.1991.tb00798.x
Subject(s) - cryptococcus neoformans , sputum , microbiology and biotechnology , cryptococcosis , serology , cryptococcus , biology , germ tube , cerebrospinal fluid , morphology (biology) , pathogenicity , pathology , virology , immunology , antibody , medicine , candida albicans , tuberculosis , zoology
Summary.Cryptococcus neoformans with a rare morphology of hand‐mirror appearance was demonstrated by direct microscopic preparation of both cerebrospinal fluid (CSF) and sputum of a patient with AIDS. In addition, one to six blasto‐conidia were seen at the tip of a germ‐tube like structure. Cr. neoformans was isolated in pure culture and the identification was confirmed by biochemical and serological tests as well as by animal pathogenicity. Zusammenfassung. Eine seltene morphologi‐sche Variante von Cryptococcus neoformans in Hand‐spiegelform wurde direktmikroskopisch sowohl im Liquor wie im Sputum eines AIDS‐Patienten nachgewiesen. Weiterhin konnten 1–6 Blastokoni‐dien an der Spitze einer keimschlauchähnlich geformten Zelle beobachtet werden. Cr. neoformans wurde in Reinkultur isoliert und biochemisch, serologisch und im Tierversuch identifiziert.