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Characterization of the Fibrinogen Binding Factor from Candida albicans and Candida tropicalis in Quantitative Immunoelectrophoresis
Author(s) -
Guinet R.,
Bruneau S.
Publication year - 1988
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/j.1439-0507.1988.tb04402.x
Subject(s) - candida tropicalis , candida albicans , microbiology and biotechnology , fibrinogen , chemistry , antigen , immunodiffusion , immunoelectrophoresis , biology , immunology , biochemistry
Summary:  The fibrinogen binding factor (FBF) was characterized in Candida albicans and Candida tropicalis reference systems by crossed immunoaffinoelectrophoresis (CIAE) with free fibrinogen in the first dimension gel. The FBF of Candida albicans and Candida tropicalis showed the same mobility and reactivity and corresponded to a cross reactive glycoproteic antigen. Thus CIAE provides a useful tool for the identification of biologically active antigens. Zusammenfassung:  Der Fibrinogen‐bindende Faktor (FBF) wurde in Candida albicans‐ und Candida tropicalis ‐Referenz‐systemen mittels gekreuzter Immunoaffinoelektrophorese (CIAE) mit freien Fibrinogen in der ersten Dimension charakterisiert. Die FBF von Candida albicans und Candida tropicalis zeigten die gleiche Motilität und Reaktivität und entsprachen einem kreuzreagierenden Glykoprotein. Die CIAE erweist sich somit als geeignetes Instrument für die Identifizierung biologisch aktiver Antigene.

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