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Dietary glutamine supplementation improves tissue antioxidant status and serum non‐specific immunity of juvenile Hybrid sturgeon ( Acipenser schrenckii ♀ × Huso dauricus ♂)
Author(s) -
Zhu Q.,
Xu Q. Y.,
Xu H.,
Wang C. A.,
Sun D. J.
Publication year - 2011
Publication title -
journal of applied ichthyology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.392
H-Index - 62
eISSN - 1439-0426
pISSN - 0175-8659
DOI - 10.1111/j.1439-0426.2011.01676.x
Subject(s) - biology , hepatopancreas , glutathione peroxidase , glutamine , sturgeon , superoxide dismutase , macrobrachium rosenbergii , medicine , malondialdehyde , antioxidant , endocrinology , juvenile , acipenser , glutathione , biochemistry , enzyme , fishery , amino acid , ecology , prawn , fish <actinopterygii>
Summary Exogenous glutamine (Gln) was evaluated for its effect on antioxidation and serum non‐specific immunity in juvenile Hybrid sturgeon ( Acipenser schrenckii ♀ × Huso dauricus ♂). Seven basal diets supplemented with 0.0, 0.3, 0.6, 0.9, 1.2, 1.5% of Gln and 1.0% alanyl‐glutamine (Aln‐Gln) were fed to fish (initial mean weight: 22.38 ± 0.18 g) for 8 weeks, and the experiment was conducted in triplicate. Treatment of fish supplemented with 1.2, 1.5% of Gln, or 1.0% of Aln‐Gln caused a significantly higher glutathione peroxidase (GPX), superoxide dismutase (SOD) activities, and glutathione (GSH) content, and lower serum malondialdehyde (MDA) levels (P < 0.05) in serum, hepatopancreas and muscles. The addition of 0.9% Gln significantly improved the serum complement‐3 (C3) and complement‐4 (C4) levels (P < 0.05). These findings suggest that diet supplementation with 0.9–1.2% Gln or 1.0% of Aln‐Gln may enhance the activity of the antioxidant defense system and the serum non‐specific immunity of juvenile Hybrid sturgeon.