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Bactericidal response of channel catfish ( Ictalurus punctatus ) by the classical and alternative complement pathways against bacterial pathogens
Author(s) -
Ourth D. D.,
Bachinski Linda M.
Publication year - 1987
Publication title -
journal of applied ichthyology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.392
H-Index - 62
eISSN - 1439-0426
pISSN - 0175-8659
DOI - 10.1111/j.1439-0426.1987.tb00449.x
Subject(s) - ictalurus , biology , catfish , vibrio anguillarum , classical complement pathway , alternative complement pathway , complement system , microbiology and biotechnology , complement (music) , antibody , immunization , innate immune system , fish <actinopterygii> , vibrio , immunology , immune system , fishery , bacteria , genetics , complementation , gene , phenotype
Summary The alternative and classical complement pathways of channel catfish ( Ictalurus punctatus ), most importantly the classical complement pathway which requires antibody, demonstrated bactericidal activity against two Gram‐negative bacterial fish pathogens, Flexibacter columnaris and Vibrio anguillarum. This shows the importance of antibody‐mediated bactericidal immunity in fish by the classical complement pathway in providing protection following immunization or natural infections.