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Preliminary Screening of Miscellaneous Compounds for their Antifertility Effects on Aedes aegypti (L.)
Author(s) -
Naqvi S. N. H.,
Ashrafi S. H.,
Rasheed S.
Publication year - 1973
Publication title -
zeitschrift für angewandte entomologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 60
eISSN - 1439-0418
pISSN - 0044-2240
DOI - 10.1111/j.1439-0418.1973.tb02273.x
Subject(s) - aedes aegypti , thiourea , chemistry , aedes , toxicology , traditional medicine , biology , organic chemistry , larva , medicine , botany
Certain compounds, synthesized in the Chemical Research Division of P.C.S.I.R. Laboratories, Karachi were tested for their antifertility effects on a pure strain of Aedes aegypti (L.), being reared in the Pesticide Section of P.C.S.I.R. Laboratories. The tests indicated that 4 compounds are better sterilants than others. Among them 1,1‐azobiscyclohexylnitrile at a dose of 5 ppm; malonamide, n‐valeramide and β ‐dimethylaminopropiohenone hydrochloride at a dose of 10 ppm produced considerable sterility. N‐skatylbenzimidazole, p‐nitrophenyl‐ β ‐dimethylaminopropionic acid, 3,6‐dichloro‐4‐methylpyridazine, 1,1‐azocyanocyclohexane, 4‐methyl‐6‐chloro‐3‐pyridazinone and 2‐aminoethylsulphuric acid at a dose of 10 ppm and 3,4,5‐trimethylbenzamide and caproamide at a dose of 100 ppm were less effective than others. Thiourea was used for comparing the antifertility effect. Zusammenfassung Untersuchungen über die Eignung organischer Verbindungen zur Sterilisierung von Aedes aegypti (L .) Neunzehn Verbindungen (Amide, Amine, Nitrile, Imidazole, Pyridazine u. a.), die in der Chem. Abteilung der P.C.S.I.R. in Karachi synthetisiert worden waren, wurden auf ihre Eignung als Sterilantien bei Aedes aegypti getestet. Gute Wirkungen zeigten: Malonamid, n‐Valeramid, 3,4,5‐Trimethylbenzamid sowie β ‐Dimethylaminopropriophenon‐hydrochlorid. Diese Stoffe werden Gegenstand weiterer Untersuchungen sein.