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Effect of experimental feed additives on aflatoxin in milk of dairy cows fed aflatoxin‐contaminated diets
Author(s) -
Kissell L.,
Davidson S.,
Hopkins B. A.,
Smith G. W.,
Whitlow L. W.
Publication year - 2013
Publication title -
journal of animal physiology and animal nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.651
H-Index - 56
eISSN - 1439-0396
pISSN - 0931-2439
DOI - 10.1111/j.1439-0396.2012.01311.x
Subject(s) - aflatoxin , total mixed ration , zoology , randomized block design , contamination , food science , chemistry , animal feed , biology , lactation , ice calving , pregnancy , agronomy , ecology , genetics
Summary Three studies were conducted to determine the potential of experimental feed additives (EFAs), clays or non‐digestible yeast oligosaccharides, to reduce milk aflatoxin (AFM 1 ) concentrations in lactating Holstein cows consuming aflatoxin‐contaminated diets. All studies included a pre‐treatment period and a 2‐week experimental period in a randomized block design. During the pre‐treatment period, cows received a total mixed ration (TMR) with no aflatoxin contamination. During both experimental weeks, all cows were fed a TMR containing aflatoxin‐contaminated corn. During experimental week 1, cows received no EFA’s in the TMR, but EFA’s were included in the TMR for the second experimental week. In studies 1 and 2, the experimental period consisted of 2 weeks each lasting 7 days with 12 cows per treatment. Aflatoxin M 1 concentrations were analysed by HPLC for milk samples collected on days 5–7 and days 11–14. In various experiments, treatments included control (no EFA), 100 g/cow daily of experimental Lallemand ® product, 10 g/cow daily of MTB‐100 ® ‐2004, (Alltech, Inc.), 10 g/cow daily of MTB‐100 ® ‐2006, (Alltech, Inc.), 10 g/cow daily of experimental Alltech ® product (Alltech, Inc.) and 227 g/cow daily of Astra‐Ben 20 ® (AB‐20 ® ; Prince Agri Products, Inc.). In study 3, the experimental period of 2 weeks each lasting 8 days and milk samples were collected from day 4 to 8 and day 11 to 16. Milk samples from study 3 were analysed for AFM 1 concentrations by ELISA. For all experiments, changes in AFM 1 concentrations because of the addition of EFA’s were calculated. Four of the five EFAs tested in this study had no significant effect on AFM 1 concentrations. However, the addition of AB‐20 ® resulted in a significant decrease in AFM 1 concentrations (60.4%). In summary, the addition of AB‐20 ® to the diet of cattle appears to be effective for significantly reducing AFM 1 concentrations in the milk of cows fed an aflatoxin‐contaminated diet.