Premium
Cobalt reduces the Δ 9 ‐desaturase index of sow milk
Author(s) -
Karlengen I. J.,
Harstad O. M.,
Kjos N. P.,
Salbu B.,
Aastveit A. H.,
Taugbøl O.
Publication year - 2011
Publication title -
journal of animal physiology and animal nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.651
H-Index - 56
eISSN - 1439-0396
pISSN - 0931-2439
DOI - 10.1111/j.1439-0396.2010.01099.x
Subject(s) - food science , cobalt , index (typography) , chemistry , zoology , biochemistry , biology , computer science , organic chemistry , world wide web
Summary The main objective of this study was to examine if cobalt (Co) reduces Δ 9 ‐desaturase indices in milk and blood lipids in sows. The experimental design consisted of a repeated measurement consisting of a pre‐treatment period of a minimum of 9 days, a treatment period of 5 days and a post‐treatment period of 6 days. Experimental animals consisted of 10 lactating sows; five sows had an intramuscular injection of 59 mg Co diluted in 5 ml 0.9% saline solution twice a day, whereas the other five had an intramuscular injection of 5 ml 0.9% saline solution twice a day as a control. Milk Δ 9 ‐desaturase indices for cis ‐9 18:1, cis ‐9 16:1 and cis ‐9 14:1 were significantly reduced (p < 0.0001) as a result of the Co‐treatment, contrasting with the plasma Δ 9 ‐desaturase indices, which were unaffected. Potential mechanisms explaining how Co might reduce milk Δ 9 ‐desaturase indices are discussed. Moreover, the toxicological level of Co and potential implications of using Co‐ethylenediaminetetraacetic acid as a liquid marker in digestibility experiments are addressed.