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A genotype probability index for multiple alleles and haplotypes
Author(s) -
Percy A.,
Kinghorn B.P.
Publication year - 2005
Publication title -
journal of animal breeding and genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.689
H-Index - 51
eISSN - 1439-0388
pISSN - 0931-2668
DOI - 10.1111/j.1439-0388.2005.00553.x
Subject(s) - genotype , index (typography) , genotyping , allele , haplotype , genetics , biology , statistics , mathematics , computer science , gene , world wide web
Summary We use linear algebra to calculate an index of information content in genotype probabilities which has previously been calculated using trigonometry. The new method can be generalized allowing the index to be calculated for loci with more than two alleles. Applications of this index include its use in genotyping strategies, strategies to manage genetic disorders and in estimation of genotype effects.