Premium
Two cases of reciprocal translocations in domestic pigs producing small litters
Author(s) -
Mäkinen A.,
Pitkänen T.,
Andersson M.
Publication year - 1997
Publication title -
journal of animal breeding and genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.689
H-Index - 51
eISSN - 1439-0388
pISSN - 0931-2668
DOI - 10.1111/j.1439-0388.1997.tb00523.x
Subject(s) - boar , litter , chromosomal translocation , biology , autosome , breed , karyotype , offspring , genetics , chromosome , andrology , zoology , sperm , veterinary medicine , pregnancy , medicine , ecology , gene
Summary Two boars of Finnish Yorkshire breed were selected for chromosomal analysis because of their small litters. One had a complex three breakpoint reciprocal translocation where the small distal chromosome segments were fused in new combinations between autosomes 2,9 and 14. This boar with a 2 n = 38,XY,t(2;9;14)(q23;q22;q25) karyotype had produced approximately 3.3 piglets per litter and its fertility was reduced by 70% compared to average of litter size in Finnish Yorkshire breed pigs. In another Finnish Yorkshire breed boar, the long arm of autosome 7 had broken and attached to the terminal end of autosome 15. The boar had a 2 n = 38,XY, rcp(7q‐;15q+)(q24;q26) karyotype. The average of piglets per litter sired by this boar was 5.2 and the litter size was reduced by approximately 50%. The chromosomal rearrangements t(2;9;14) was inherited by four of the boar's offspring studied from two whole litters having seven piglets altogether. Meiotic chromosomes were analysed conventionally from one male translocation carrier offspring of the t(2;9;14) boar. Total sperm count and progressive motility of spermatozoa were within normal limits in one male translocation carrier offspring of the t(2;9;14) boar and in the rcp(7q‐;15q+) boar. The two reciprocal translocations seem to have arisen spontaneously in these two boars. Zusammenfassung Zwei Fälle reziproker Translokationen bei Ebern mit kleinen Nachkommen Würfen Von zwei Finnischen Yorkshire Ebern hatte einer drei komplexe reziproke Translokationen, wo kurze distale Chromosomensegmente zu neuen Kombinatioenen zwischen Autosomen 2, 9 und 14 fusioniert waren. Der Eber mit 2n = 38,XY,t(2;9;14)(q23;q22;q25) Karyotyp hatte Nachkommenwürfe mit etwa 3.3 Ferkel weniger und 70% Fruchtbarkeit der bei dieser Rasse normalen. In einem anderen Eber war der lange Arm von Chromosom 7 gebrochen und am Ende von Chromosom 15: 2n = 38,XY, rcp(7q‐; 15q+)(q24;q26) Karyotyp. Nachkommenwurfgröße war 5.2. Das chromosomale Rearrangement t(2;9;14) wurde an 4 Nachkommen in zwei Würfen mit zusammen 7 Ferkel vererbt. Meiotische Chromosomen wurden bei einem männlichen Translokationsträger dieser Nachkommen analysiert. Gesamtspermienenzahl und ihre Vorwärtsbewegung waren in normalen Grenzen bei diesem Nahkommen ebenso wie beim rcp(7q‐;15q+) Eber. Die zwei reciproken Translokationen scheinen spontan entstanden zu sein.