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Total anti‐oxidant status: a biochemical predictor of human male fertility
Author(s) -
Adeel A. L.,
Jahan S.,
Subhan F.,
Alam W.,
Bibi R.
Publication year - 2012
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/j.1439-0272.2010.01131.x
Subject(s) - semen , andrology , male infertility , fertility , sperm , sperm motility , infertility , population , semen analysis , male fertility , biology , oligospermia , gynecology , physiology , medicine , pregnancy , environmental health , genetics
Summary The objective of the study was to assess whether seminal plasma total antioxidant status (TAS) can be used as a biochemical predictor of male fertility and its variation in different categories of infertile male subjects in our population. The study population consisted of 28 fertile and 127 infertile [teratozoospermic (30), asthenoteratozoospermic (30), azoospermic (21), oligoastheno‐teratozoospermic (20), polyzoospermic (15) and oligozoospermic (11)] male subjects. Seminal plasma was separated by centrifugation and stored at minus 80 degree Celsius. Semen was analysed using computer‐assisted semen analysis according to WHO criteria. Seminal plasma TAS was estimated by colorimetric method using Randox total antioxidant status kit. TAS of fertile male subjects was significantly ( P < 0.001) higher than that of infertile patients. In whole studied population, seminal plasma TAS showed a significant positive correlation with sperm concentration ( P < 0.001), sperm motility ( P < 0.0001), and spermatozoa with normal morphology ( P < 0.0001). In conclusion, this study suggests that TAS of seminal plasma is one of the important factors contributing to male infertility, and it can be used as a biochemical predictor for male fertility.