Dramatic improvement of penile venous leakage upon testosterone administration. A case report and review of literature

Summary The main effect of testosterone was long‐time assumed to be on sexual interest and, indirectly, on erectile function. Newer insights demonstrate that testosterone deficiency impairs the anatomical, ultrastructural, biological and physiological/functional substrate of penile erection, which can be, at least in part, restored by normalization of plasma testosterone levels. This is a report on a 56‐year‐old man suffering from diabetes mellitus type II and metabolic syndrome, who had complaints of a severe erectile dysfunction because of venous leakage, confirmed by pharmaco‐cavernosography. He was also testosterone deficient (1.8 ng ml −1 ). Upon testosterone administration his erectile function improved dramatically. Repeated cavernosography no longer showed venous leakage.