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The hypophyseal‐testicular axis and sex accessory glands following chemical sympathectomy with guanethidine of pre‐pubertal to mature rats
Author(s) -
Kempinas W. G.,
Petenusci S. O.,
Silva A. A. M. Rosa,
Favaretto A. L. V.,
Carvalho T. L. Lamano
Publication year - 2009
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/j.1439-0272.1995.tb01081.x
Subject(s) - endocrinology , medicine , guanethidine , seminal vesicle , testosterone (patch) , ejaculation , luteinizing hormone , testosterone propionate , fructose , hormone , prostate , chemistry , biology , androgen , cancer , stimulation , biochemistry
Summary Selective chemical sympathectomy of the internal sex organs of prepubertal to mature male Wistar rats was performed by chronic treatment with low doses of guanethidine. Plasma testosterone and luteinizing hormone and the intratesticular level of testosterone were determined. The weight and fructose content of seminal vesicle and ventral prostate were also investigated. The results showed that sympathetic innervation is related to the control of the hypophyseal‐testicular axis as well as to the growth and potential secretory activity of the male sex accessory glands.