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The sperm penetration test (P‐test) can predict fecundability in the male partner from infertile couples
Author(s) -
Bostofte E.,
Bagger P.,
Michael A.,
Stakemann G.
Publication year - 2009
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/j.1439-0272.1992.tb02624.x
Subject(s) - semen , sperm , semen analysis , infertility , male infertility , gynecology , fertility , andrology , biology , proportional hazards model , medicine , pregnancy , population , genetics , environmental health
Summary. Three hundred and twenty‐one consecutive couples were investigated for infertility at Hvidovre University Hospital in the period from November 1977 to June 1985. The male partners were evaluated in two ways: the classical semen analysis, and the ability of sperm to penetrate fresh hen egg white, the P‐test. A Cox regression analysis was used to describe the relation between these variables and fecund‐ability, i.e. the time required to conceive. Four of thirteen variables—the number of morphologically normal spermatozoa, the number of motile spermatozoa, the P‐test, and the man's age—each have significant relation to the fecund‐ability. However, when covariation is considered, only the P‐test and the man's age posses significant prognostic information, whereas the variables of the classical semen analysis do not. This indicates that the P‐test may replace the classical semen analysis when trying to predict individual pregnancy probabilities. Finally, the P‐test and the man's age are combined to form a prognostic index which predicts the fecundability of the male partner in the individual infertile couple.