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Seminal parameters of ejaculates collected successively with sixty minute interval in infertile men: effect of combination of prazosin and terbutaline on these parameters
Author(s) -
Gülmez I.,
Tathşen A.,
Karacagil M.,
Kesekci S.
Publication year - 2009
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/j.1439-0272.1991.tb02526.x
Subject(s) - ejaculation , prazosin , terbutaline , sperm , sperm motility , andrology , motility , semen , medicine , endocrinology , biology , antagonist , receptor , asthma , genetics
Summary. Out of 37 infertile men, 33 who were able to give two ejaculates by masturbation successively with a sixty minute interval, were studied. There was no significant change in sperm density in the second ejaculation whereas seminal volume decreased ( P < 0.01) and sperm motility increased ( P < 0.05) significantly. After a seven‐day treatment with combination of prazosin (α 1 ‐blocker) and terbutaline (β 2 ‐stimulator), the same successive ejaculates were obtained from only 27 of these patients. In this case sperm density and motility changed insignificantly, whereas seminal volume again decreased ( P < 0.01) significantly. The changes in seminal parameters were not significant between the pre‐ and post‐treatment first specimens and between the pre‐ and post‐treatment second ones. In a short‐term study there are not any alterations to observe. The favourable results with a long‐term treatment, published by Japanese authors, require a confirmation by further studies.