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Ion‐Exchange Chromatography of Amino Acids in Ejaculates of Diabetics
Author(s) -
KAEMMERER H.,
MITZKAT H.J.
Publication year - 2009
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1111/j.1439-0272.1985.tb01046.x
Subject(s) - phenylalanine , amino acid , leucine , histidine , glutamine , serine , biochemistry , glycine , tyrosine , chemistry , threonine , methionine , ion chromatography , alanine , valine , catabolism , metabolism , enzyme
Summary: 30 amino acids and their derivatives could be found in the ejaculates of humans by ion‐exchange chromatography. There were significant differences between diabetics and controls in the levels of theonine, serine, glutamine, glycine, iso‐leucine, leucine, tyrosine, phenylalanine, histidine and in 3‐methyl‐histidine. There was a positive correlation between levels of certain amino acids and the number of pathologically motile spermatozoa, particularly microforms and head alterations. An impaired Krebs cyclus function may explain an elevation of amino acid levels as they are utilized mainly by this cycle, which function depends on intact substrate flow from glucose catabolism.