Premium
The Small Intestine of the Adult New Hampshire Chicken: an Immunohistochemical Study
Author(s) -
Pirone A.,
Ding B. A.,
Lenzi C.,
Baglini A.,
Giannessi E.,
Romboli I.
Publication year - 2011
Publication title -
anatomia, histologia, embryologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 35
eISSN - 1439-0264
pISSN - 0340-2096
DOI - 10.1111/j.1439-0264.2010.01055.x
Subject(s) - duodenum , ileum , jejunum , enteroendocrine cell , small intestine , medicine , glucagon , gastric inhibitory polypeptide , immunohistochemistry , endocrinology , pancreas , biology , gastrointestinal tract , pancreatic polypeptide , endocrine system , hormone
With 3 figures Summary The presence and distribution of glucose‐dependent insulinotropic polypeptide or gastric inhibitory polypeptide (GIP), gastric‐releasing peptide (GRP) and glucagon immunoreactivity were studied in the small intestine of the New Hampshire chicken using immunohistochemistry. This is the first report of the presence of GIP‐immunoreactive (ir) cells in avian small intestine. GIP, GRP and glucagon immunoreactivity was localized in the epithelium of the villi and crypts of the duodenum, jejunum and ileum. In particular, both in the duodenum and in the jejunum immunoreactive endocrine cells to GIP, GRP and glucagon were observed. In the ileum, we noticed GIP‐ir and glucagon‐ir cells. GRP‐ir was found in nerve fibres of all three segments of the small intestine. The distribution of these bioactive agents in the intestinal tract of the chicken suggests that GIP and glucagon may play a role in the enteropancreatic axis in which intestinal peptides modulate pancreas secretion.