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Expression of AMH in Female Fetal Intersex Gonads in the Bovine
Author(s) -
Cabianca G.,
Rota A.,
Cozzi B.,
Ballarin C.
Publication year - 2007
Publication title -
anatomia, histologia, embryologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 35
eISSN - 1439-0264
pISSN - 0340-2096
DOI - 10.1111/j.1439-0264.2006.00713.x
Subject(s) - fetus , biology , andrology , expression (computer science) , medicine , endocrinology , genetics , pregnancy , computer science , programming language
Summary Anti Müllerian Hormone, AMH, is believed to be the main agent in the freemartin syndrome. Supposing an active role of freemartin gonads in AMH secretion, in the present study, we aimed at investigating the presence and the localization of AMH producing cells either in fetal or in adult freemartin gonads. Our finding of positive AMH cells in a 26‐week‐old freemartin fetus indicates an active role of masculinized freemartin gonads in AMH secretion. However, the positive reaction, limited to few cells grouped in ‘nests’ in proximity to testis cord‐like structures, supports a chimeric origin of such cells, migrated from the male co‐twin. No adult freemartin, irrespective from the degree of masculinization, showed any AMH positive cell.