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The Distribution of Calcitonin Gene‐Related Peptide in Gastric Vagal Circuit of Rats
Author(s) -
Lee H. S.,
Lee I. S.,
Kang T.C.,
Seo J.,
Lee B. H.
Publication year - 1998
Publication title -
anatomia, histologia, embryologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 35
eISSN - 1439-0264
pISSN - 0340-2096
DOI - 10.1111/j.1439-0264.1998.tb00203.x
Subject(s) - calcitonin gene related peptide , vagus nerve , retrograde tracing , pseudorabies , dorsal motor nucleus , nucleus , nucleus ambiguus , area postrema , immunohistochemistry , biology , calcitonin , medicine , endocrinology , neuroscience , neuropeptide , virus , receptor , central nervous system , medulla oblongata , immunology , stimulation
Summary In the present study, we performed the retrograde tracing method using the neurotropic pseudorabies virus bartha strain (PRV‐Ba) and immunohistochemistry against CGRP, to identify whether CGRP exists in the gastric monosynaptic vagal circuit between dorsal motor nucleus of vagus nerve (DMV) and nucleus tractus solitarius (NTS). At the results, PRV immunoreactive neurons were found in both DMV and NTS. However, CGRP‐immunoreactive cells were present only in NTS, which contained no double‐labeled neurons for PRV and CGRP. These results suggest that CGRP may not have a neuronal function in gastric vagal circuit of rat.