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Immunohistochemical Colocalization of Serotonin, Substance P and Met‐enkephalin‐Arg 6 ‐Gly 7 ‐Leu 8 in the Endocrine Cells of the Ruminant Duodenum
Author(s) -
Mimoda T.,
Kitamura N.,
Hondo E.,
Yamada J.
Publication year - 1998
Publication title -
anatomia, histologia, embryologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 35
eISSN - 1439-0264
pISSN - 0340-2096
DOI - 10.1111/j.1439-0264.1998.tb00158.x
Subject(s) - enteroendocrine cell , serotonin , substance p , endocrine system , colocalization , medicine , duodenum , endocrinology , biology , immunohistochemistry , enkephalin , neuropeptide , microbiology and biotechnology , biochemistry , hormone , receptor , opioid
Summary The duodenum of various ruminants was examined by immunohistochetnical staining for serotonin, substance P and Metenkephalin‐Arg 6 ‐Gly 7 ‐Leu 8 (MENK8). Serotonin‐ and substance P‐immunoreactive endocrine cells were detected in samples from cow, calf, sheep, goat, and barbary sheep. MENK8‐immunoreactive endocrine cells were detected exclusively in samples from cow and calf. Substance P and MENK8 immunoreactivity was found in serotonin‐immunoreactive endocrine cells of cattle. Substance P‐ and MENK8‐immunoreactive nervous elements were detected in all ruminants examined. The present results suggest that the expression and/or the mechanism that controls the expression of each peptide might differ between endocrine cells and nerve cells and might also depend on animal species.