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Electron Microscopic Examination of the Developing Bovine Glomerular Filtration Barrier
Author(s) -
Canfield P. J.
Publication year - 1981
Publication title -
anatomia, histologia, embryologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 35
eISSN - 1439-0264
pISSN - 0340-2096
DOI - 10.1111/j.1439-0264.1981.tb00503.x
Subject(s) - basement membrane , microbiology and biotechnology , electron microscope , glomerular basement membrane , podocyte , fetus , endothelium , transmission electron microscopy , filtration (mathematics) , biology , membrane , chemistry , pathology , biophysics , anatomy , kidney , endocrinology , medicine , materials science , pregnancy , glomerulonephritis , nanotechnology , biochemistry , proteinuria , optics , physics , genetics , statistics , mathematics
Observations on the development of the bovine glomerular filtration barrier, with particular emphasis on the roles of the podocytes and endothelial cells, are presented. For this purpose, tissue from metanephroi of embryos and foetus and from kidneys of adult cows were examined with the transmission electron microscope. It was concluded that the endothelium and podocytes were dependent on one another for differentiation, and that once differentiated, they both contributed to basement membrane production.