Open AccessPlasma exchange in a patient with primary antiphospholipid syndrome undergoing kidney transplantation
Author(s) -
Ruffatti Amelia,
Marson Piero,
Valente Marialuisa,
Ciprian Manuela,
Tonello Marta,
Marchini Francesco,
Cozzi Emanuele,
Rigotti Paolo
Publication year - 2007
Publication title -
transplant international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 82
eISSN - 1432-2277
pISSN - 0934-0874
DOI - 10.1111/j.1432-2277.2007.00454.x
Subject(s) - medicine , transplantation , thrombosis , kidney transplantation , antiphospholipid syndrome , renal vein thrombosis , surgery , population , hemodialysis , lupus anticoagulant , warfarin , thrombophilia , nephrotic syndrome , environmental health , atrial fibrillation
Early graft thrombosis remains the most frequent cause of renal graft failure in patients with antiphospholipid syndrome (APS) . Several authors have reported that anticoagulation begun before or at the time of kidney transplantation reduces post-transplant thrombosis. Nonetheless, despite anticoagulant therapy, graft thrombosis takes place in 40% of the APS population [7] and the appropriate treatment strategy to utilize in these patients is unclear.\udThe present study is a case report on a patient with primary APS who, while receiving prophylaxis with plasma exchange (PE) in addition to full anticoagulation therapy, underwent a successful living-donor kidney transplantation