Open AccessSingle breath exhaled nitric oxide in lung transplant patients: a preliminary clinical study
Author(s) -
Zegdi RACHID,
Guillmain ROMAIN,
Amrein CATHERINE,
Chevalier PATRICK,
Lajos PAUL,
Couëtil JEANPAUL,
Carpentier ALAIN,
Fabiani JEANNOËL
Publication year - 1999
Publication title -
transplant international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.998
H-Index - 82
eISSN - 1432-2277
pISSN - 0934-0874
DOI - 10.1111/j.1432-2277.1999.tb00620.x
Subject(s) - medicine , exhaled nitric oxide , lung transplantation , nitric oxide , exhalation , lung , intensive care medicine , gastroenterology , lung function , anesthesia
Exhaled nitric oxide is considered as a marker of airway inflammation. We report here our preliminary experience with single‐breath exhaled nitric oxide measured in lung transplant patients with and without bronchiolitis obliterans syndrome and in cardiac transplant patients. Peak and end‐expiratory nitric oxide concentrations did not differ between groups, but single‐breath exhaled nitric oxide recordings were strikingly different in patients suffering from bronchiolitis obliterans syndrome, with a slower decrease from peak to end‐expiratory nitric oxide concentration. Further studies are required in order to determine whether theses abnormalities reflect the inflammatory process of bronchiolitis obliterans syndrome.