Open AccessPrimary Structure of Stallion Seminal Plasma Protein HSP‐7, a Zona‐Pellucida‐Binding Protein of the Spermadhesin Family
Author(s) -
Reinert Markus,
Calvete Juan J.,
Sanz Libia,
Mann Karlheinz,
TöpferPetersen Edda
Publication year - 1996
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1996.0636r.x
Subject(s) - zona pellucida , boar , protein primary structure , zona pellucida glycoprotein , biology , protein family , microbiology and biotechnology , semen , andrology , peptide sequence , oocyte , genetics , gene , embryo , medicine
The primary structure of HSP‐7, a 14‐kDa protein isolated from stallion seminal plasma, has been determined. HSP‐7 belongs to the spermadhesin protein family, shares 98% sequence identity with the boar seminal plasma protein AWN, and, like its boar homolog, displays zona‐pellucida‐binding activity. Despite these conserved structural and functional features, the equine and porcine spermadhesins differ in their topography on spermatozoa.