Open AccessEffects of the Xenopus laevis mitochondrial single‐stranded DNA‐binding protein on the activity of DNA polymerase γ
Author(s) -
MIGNOTTE Bernard,
MARSAULT Janine,
BARATGUERIDE Monique
Publication year - 1988
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1988.tb14123.x
Subject(s) - xenopus , mitochondrial dna , dna clamp , dna polymerase , polymerase , biology , microbiology and biotechnology , dna , dna replication , dna polymerase ii , biophysics , chemistry , biochemistry , polymerase chain reaction , gene , reverse transcriptase
The single‐stranded DNA‐binding protein from Xenopus laevis oocyte mitochondria, which has been found associated with the D loop, binds to ssDNA in stoichiometric amounts and can under certain conditions stimulate the activity of the DNA polymerase γ. Its properties suggest that it is involved in strand displacement during the replication of the mitochondrial genome.