Open AccessFundamental relationships for the effect of proton dissociation equilibria on enzymic reaction steps
Author(s) -
PETTERSSON Gösta
Publication year - 1987
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1987.tb13497.x
Subject(s) - protonation , dissociation (chemistry) , chemistry , catalysis , proton , ionization , dissociation constant , reaction rate , reaction rate constant , computational chemistry , equilibrium constant , thermodynamics , photochemistry , kinetics , organic chemistry , biochemistry , physics , ion , classical mechanics , nuclear physics , receptor
Relationships have been derived which describe the pH dependence contributed to rate and equilibrium constants for an arbitrary enzymic reaction step by the ionization of an enzymic group or non‐enzymic reactant when both protonation states of the ionizing species are assumed to participate in the catalytic reaction.