Open AccessQuaternary Structure and Spin Equilibria in Ferric Hemoglobins
Author(s) -
NOBLE Robert W.,
YOUNG Alice,
IORIO Ernesto,
WINTERHALTER Kasper H.,
CERDONIO Massimo,
MORANTE Silvia,
VITALE Stefano
Publication year - 1983
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1983.tb07488.x
Subject(s) - methemoglobin , protein quaternary structure , quaternary , magnetic moment , carp , ferric , azide , hemoglobin , chemistry , moment (physics) , spin (aerodynamics) , nuclear magnetic resonance , condensed matter physics , materials science , thermodynamics , inorganic chemistry , physics , biology , organic chemistry , fishery , quantum mechanics , biochemistry , paleontology , protein subunit , fish <actinopterygii> , gene
The effective magnetic moments for a number of human and carp methemoglobin derivatives were determined in solution at room temperature. The data permit us to confirm the dependence of the spin‐state equilibrium of azide methemoglobin on the quaternary state of the hemoglobin and to demonstrate a similar dependence for both human and carp aquomethemoglobin. In addition, the pH dependence of the effective magnetic moment and the Soret spectrum of carp azide‐methemoglobin are compared.