Open AccessStructural Studies of the Lipopolysaccharide from Salmonella typhimurium 902 (Collb drd2)
Author(s) -
HOFFMAN James,
LINDBERG Bengt,
GLOWACKA Maria,
DERYLO Mieczyslawa,
LORKIEWICZ Zbigniew
Publication year - 1980
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1980.tb04479.x
Subject(s) - lipopolysaccharide , salmonella , bacteria , microbiology and biotechnology , mutant , plasmid , chemistry , biology , biochemistry , genetics , gene , endocrinology
Salmonella typhimurium infected with the plasmid Collb drd2 gave rise to changes in the composition of the bacterial lipopolysaccharide. Bacteria carrying the wild‐type Collb, the revertant of drd2 to the wild type, or the noncolicinogenic strain resulting from the elimination of Collb drd2, showed no changes in the sugar composition of the lipopolysaccharide. The structure of the O‐specific side chains of the lipopolysaccharide produced by S. typhimurium 902, infected with derepressed Collb mutants has been investigated. As a result of these studies, it is proposed that the O‐specific side chains are composed of chemical repeating units with the following structure: