Open AccessThe Complete Amino‐Acid Sequence of Histone H2B from the Mollusc Patella granatina
Author(s) -
HELDEN Paul D.,
STRICKLAND Walter N.,
BRANDT Wolf F.,
HOLT Claus
Publication year - 1979
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1979.tb12796.x
Subject(s) - histone h2b , histone , histone octamer , amino acid , protein primary structure , chemistry , biochemistry , peptide sequence , histone h1 , biology , nucleosome , dna , gene
1. From the marine mollusc, Patella granatina , a histone has been isolated. Its primary structure has been established and it has been designated histone H2B patella . It consists of a polypeptide chain of 121 amino acids. 2. In the carboxy‐terminal two thirds of the molecule there is a high degree of sequence homology to the corresponding region in calf histone H2B with identical residues in 95% of the positions. 3. In the N‐terminal 22 amino acids histone H2B patella differs considerably from the mammalian histone H2B and it is shorter by four residues.