Open AccessControl of Teichoic Acid Synthesis in Bacillus licheniformis ATCC 9945
Author(s) -
HUSSEY Helen,
SUEDA Satoru,
CHEAH SuanChoo,
BADDILEY James
Publication year - 1978
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1978.tb12008.x
Subject(s) - bacillus licheniformis , teichoic acid , bacillus (shape) , biology , microbiology and biotechnology , bacillus subtilis , chemistry , bacteria , biochemistry , enzyme , genetics , peptidoglycan
Analysis of cell walls of Bacillus licheniformis ATCC 9945 grown under phosphate limitation showed that teichoic acid could be replaced by teichuronic acid under these conditions. Teichuronic acid, however, was always present in the walls to some extent irrespective of the growth conditions. The enzymes involved in teichoic acid synthesis were investigated and the synthesis of these was shown to be repressed when the intracellular P i level fell. CDP‐glycerol pyrophosphorylase was studied in some detail and evidence is presented to shown that the enzyme is inactivated under phosphate‐limited conditions. The mechanism of inactivation is unknown but it has been shown that it does not require protein synthesis de novo .