Open AccessStructural Studies of the Shigella flexneri Variant X, Type 5a and Type 5b O‐Antigens
Author(s) -
KENNE Lennart,
LINDBERG Bengt,
PETERSSON Kurt,
KATZENELLENBOGEN Ewa,
ROMANOWSKA Elzbieta
Publication year - 1977
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1977.tb11599.x
Subject(s) - shigella flexneri , antigen , tetrasaccharide , shigella , oligosaccharide , type (biology) , alpha (finance) , stereochemistry , microbiology and biotechnology , chemistry , biology , bacteria , biochemistry , mathematics , escherichia coli , genetics , salmonella , polysaccharide , ecology , construct validity , statistics , gene , psychometrics
Previous studies of different Shigella flexneri O‐antigens indicate that their O‐specific region is composed of oligosaccharide repeating units containing a basic tetrasaccharide structure, to which α‐ d ‐glucopyranosyl groups and O ‐acetyl groups may be attached to different positions. Structural studies of O‐antigens from variant X, type 5a and type 5b lend further support to this assumption. These antigens contain terminal α‐ d ‐glucopyranosyl groups, one each per repeating unit in X and 5a, two in 5b. The location of these groups in the repeating unit has been determined.