Open AccessThe Virtual Absence of Antigenic Cross‐Reactivity between Functionally Distinct Trout Hemoglobins
Author(s) -
TANWILSON Anna L.,
REICHLIN Morris,
BRUNORI Maurizio,
NOBLE Robert W.
Publication year - 1976
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1976.tb11097.x
Subject(s) - salmo , rainbow trout , affinities , biology , trout , bohr effect , ligand (biochemistry) , antigen , cross reactivity , zoology , reactivity (psychology) , chemistry , genetics , evolutionary biology , fish <actinopterygii> , biochemistry , hemoglobin , cross reactions , fishery , receptor , oxygen–haemoglobin dissociation curve , medicine , alternative medicine , pathology
The antigenic properties of the hemoglobins of two species of rainbow trout, Salmo irideus and Salmo gairdneri , have been compared. Each of these species possess two different classes of hemoglobins, the members of the first of which have no Bohr effect while those of the second exhibit a pronounced pH dependence of their ligand affinities. The hemoglobins from these two species are antigenically indistinguishable. However, between the two classes of hemoglobins there is almost no immunological cross‐reactivity.