Open AccessStructural Studies on O‐Specific Polysaccharide of Shigella flexneri Serotype 6
Author(s) -
KATZENELLENBOGEN Ewa,
MULCZYK Marian,
ROMANOWSKA Elžbieta
Publication year - 1976
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1976.tb10011.x
Subject(s) - shigella flexneri , serotype , microbiology and biotechnology , polysaccharide , shigella , biology , bacteria , salmonella , escherichia coli , biochemistry , genetics , gene
O‐specific chain of Shigella flexneri 6 lipopolysaccharide was found to be composed mainly of rhamnose, N‐acetylgalactosamine and O‐acetyl groups in molar ratio 2.2 : 1.0 : 0.64, respectively. The presence of N‐acetylgalactosamine, a distinguished feature of the lipopolysaccharide from serotype 6 was proved by several methods. The following tentative structure for the repeating unit of Sh. flexneri 6 O‐specific chain has been proposed:From the serological studies it could be concluded that β‐ l ‐rhamnosyl‐1,3‐N‐acetyl‐ d ‐galactosaminyl sequence is involved in the type VI specificity, but the presence of O‐acetyl and N‐acetyl groups is not a necessary condition for it.